Real-Time Cell Sorting with FPGA-Accelerated Deep Learning

Real-Time Cell Sorting with Scalable In Situ FPGA-Accelerated Deep Learning

This work presents a teacher-student ML framework using knowledge distillation for label-free lymphocyte classification (T4, T8, B cells) from bright-field images, deployed on FPGA with ultra-low 14.5 µs inference latency - 40× faster than previous state of the art.

November 2025 · Khayrul Islam, Ryan F. Forelli, Jianzhong Han, Deven Bhadane, Jian Huang, Joshua C. Agar, Nhan Tran, Seda Ogrenci, Yaling Liu
Multiplex Image Machine Learning (MIML)

MIML: Multiplex Image Machine Learning for High Precision Cell Classification via Mechanical Traits within Microfluidic Systems

This paper presents a novel machine learning framework (MIML) that enhances the precision and specificity of cell classification by integrating label-free cell images with biomechanical data, achieving a 98.3% classification accuracy.

March 2025 · Khayrul Islam, Ratul Paul, Shen Wang, Yuwen Zhao, Partho Adhikary, Qiying Li, Xiaochen Qin, Yaling Liu